I recently had some issues with my ZoneAlarm install and MS Outlook 2003 and the Anti-Spam plug-in. Whenever I launched Outlook, the ZoneAlarm plugin was not initializing despite efforts to enable (through ZA and through the COM add-in within Outlook). I found a solution that seems to have worked. Basically, you need to fully delete the COM add-in and then recreate from scratch. To do this, just follow the following steps:
1) Open “Tools->Options…”
2) Click on the “Other” tab.
3) Click on “Advanced Options’.
4) Click on “COM Add-Ins”
5) Remove “MailBuddy Outlook Addin”
6) Add “MailBuddy Outlook Addin” it back in by choosing “C:\Program Files\Zone Labs\ZoneAlarm\MailFrontier\mlfoshim.dll”
Then you should be good to go!